Contrato a cargo de proyecto == Postdoctoral # 1 (IDIBAPS & ICREA, Barcelona): "Role of plasticity factors ZEB1 and ZEB2 in macrophages in the tumor microenvironment"

Job Offer: Postdoctoral Position (TAMs/Macrophages/Cancer). Group of Gene Regulation of Cellular Plasticity & Differentiation in Inflammation and Cancer (IDIBAPS & ICREA, Barcelona, Spain)

Link: https://www.icrea.cat/sites/default/files/researchers/researcher-sections/posdoc_offer-tams_2021.pdf

The Group of Gene Regulation of Cellular Plasticity & Differentiation in Inflammation and Cancer (IDIBAPS & ICREA, Barcelona, Spain ) has obtained funding from the Agencia Estatal de Investigacion (National Research Agency/Ministry of Science and Innovation) to fund a postdoc position.

The selected candidate will work on the role of the plasticity EMT factors ZEB1 and ZEB2 in macrophages during cancer (tumor-associated macrophages in colorectal cancer, ovarian cancer, melanoma). The ZEB1 and ZEB1 factors play key roles in homeostasis and disease regulating stemness (normal/cancer stem cells), differentiation, tissue regeneration, and tumor initiation and progression. The successful candidate will join a dynamic and international group of postdoc and PhD students in a leading research center in downtown Barcelona.

The project will make use of a wide array of state-of-the-art techniques, and in vitro and in vivo approaches including unique transgenic mouse models and high-throughput and OMICs technologies.

REQUIREMENTS

Essential Requirements
★ PhD degree in Biology or related biomedical discipline obtained not earlier than January 2019.
★ Strong publication record with at least 2-3 first-author articles in high impact journals
★ Solid background in Molecular and Cellular Biology.
★ Experience in mouse models

Desirable Experience
Candidates with proven experience in any of the following topics will receive higher consideration in the selection process: macrophage biology (acute/chronic inflammation, cancer) molecular oncology, metabolism, epigenetics, transcriptomics, and/or bioinformatics.

CONDITIONS
The project has been already funded and the position is available immediately. The salary will be commensurate with the expertise and the publication record.

ADDITIONAL INFORMATION & APPLICATIONS
For further information about the work in the group visit https://bit.ly/34r2VXT & https://bit.ly/3zWD3DG Applications should include: a) complete CV, b) the names and contact details of three researchers that have supervised the candidate’s work. Additional inquiries and applications should be sent to: idibaps.postigo3 en gmail.com indicating “Postdoc Call TAMs 2022” in the subject of the email.

SELECTED PUBLICATIONS (recent articles as corresponding author)
★ Gut 66:666. IF: 23.0
★ Gut 68:2129. IF: 23.0
★ Nature Commun 10:1364. IF: 14.9
★ Nature Commun 9:2424. IF: 14.9

★ Nature Commun 5:5660. IF: 14.9

★ Nature Commun 4:2650. IF: 14.9
★ Sci Advances 7:abd7455 IF: 14.1
★ Nucleic Acids Res 46:10697. IF: 16.9
★ Cell Death Differ 21:247. IF:15.8

★ Clin Cancer Res 19:1071. IF: 12.7
★ EMBO J 36:3336. IF: 11.6