PhD research contract in “Theragnostic targeting MMPS and BBB after stroke”
A predoctoral research position is available at the Achucarro Basque Center for Neuroscience under the supervision of Dr. Abraham Martín in the Neuroimaging and Biomarkers of Inflammation Lab to do the PhD thesis. The position has a duration of 3 years, starting on June 1st, 2023 (at the latest).
The project will be developed within the recently granted ERANET Neuron project IMatrix (https://www.neuron-eranet.eu/wp-content/uploads/Neuron-NL41-Jan23_final.pdf). The main goal of the PhD project will be the exploration and validation of the diagnostic and therapeutic potential of MMPs using smart 19F nanoprobes after preclinical stroke. The candidate will participate in a translational project, in the frame of an international consortium involving experts from Spain, France, Germany and Hungary, aimed to investigate the role of matrix metalloproteinases (MMPs) on the secondary ischemic damage and blood-brain barrier (BBB) dysfunction. The project will use stroke models in rodents and a battery of molecular imaging techniques (Positron emission tomography (PET), Magnetic resonance imaging (MRI), Confocal and 2-Photon microscopy) together with application of nanoprobes, ex vivo molecular biology, and immunohistochemical techniques.
Applicants must have a degree in Biology, biochemistry or similar and a Master that gives access to PhD programs. Background in animal models, imaging sciences and biomedicine will be positively valued. Applicants should have a good academic record, good communication skills, a strong passion and commitment to science, and work well within a group. Knowledge of written and spoken English is also needed.
Applications should be addressed to Dr. Abraham Martín and sent via e-mail with the subject ‘IMatrix position’ to Abraham.martin en achucarro.org. They must include:
1. a cover letter highlighting their interest in the position and the main research achievements.
2. curriculum vitae clearly stating the degree and master final qualifications.
3. the name and contact address (e-mail) of at least one academic referee.
Applications will be considered upon arrival and the selection process will end once the position is filled.